Capoten side effects.

Capoten side effects.

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No preion Capoten.

Latin name: Capoten
Pharmacological groups: inhibitors APF
Nozologicheskaya classification (ICD-10): I10-I15 Diseases of the circulatory system. I25.2 carry in the past myocardial infarction. I50 heart failure. I50.0 congestive heart failure. N08.3 Chronic lung injury with diabetes mellitus. N15 Other diseases tubulointerstitsialnye kidney
Pharmacological effects
"cheap 37 5 Capoten" - Active ingredients (INN) Kaptopril (Captopril)
Application: arterial hypertension (mono-and combination therapy), congestive heart failure, cardiomyopathy, a violation of left ventricular function at a stable condition in patients after myocardial infarction forward, diabetic nephropathy against the backdrop of diabetes mellitus type 1 (albuminuria with more than 30 mg / day).

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Contraindications: Giperchuvstvitelnost, anamnesticheskih availability of information on the development of edema Kvinke with previous appointment inhibitors APF, hereditary or idiopathic edema Kvinke, primary giperaldosteronizm, pregnancy, breast-feeding.

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Restrictions to use: Assessing the risk-benefit ratio is needed in the following cases: leukopenia, thrombocytopenia, aortic stenosis, or changes etc. obstruktivnye impeding outflow of blood from the heart, hypertrophic cardiomyopathy with low cardiac output, expressed breach of kidney function; bilateral renal artery stenosis or stenosis artery single kidney, kidney-set existence; hyperpotassemia; childhood.

The use during pregnancy and breastfeeding: contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Side steps: From the nervous system and sensory organs: fatigue, dizziness, headache, central nervous system depression, drowsiness, confusion, depression, ataxia, convulsions, or pricking sensation of numbness in the limbs, visual impairment and / or smell.
On the part of the cardiovascular system and blood (blood, hemostasis): hypotension, including canting, angina, myocardial infarction, heart rhythm violation (auricular tachy-or bradycardia, ciliary arrhythmia), heartbeat, severe violation of cerebral circulation, peripheral edema, lymphadenopathy, anemia, pain in the chest, tromboemboliya pulmonary artery, NEUTROPENIA agranulocytosis (0, 2% - in patients with kidney function violation, 3.7% - against a backdrop of kollagenozov), thrombocytopenia, eosinophilia.
On the part of the respiratory system: bronhospazm, breathlessness, interstitial pneumonia, bronchitis, dry nonproductive cough.
For part of the alimentary canal: anorexia, a breach of taste, stomatitis, ulcerous lesions of mucous membrane of the mouth and stomach, kserostomiya, GLOSS, difficulty swallowing, nausea, vomiting, dyspepsia, flatulence, abdominal pain, constipation or diarrhea, pancreatitis, liver failure (holestaz , Cholestatic hepatitis, hepatocellular necrosis).
On the part of the digestive system: disruption of kidney oliguriya, proteinuria, impotence.
On the skin: skin redness, rash, itching, eksfoliativny dermatitis, toxic epidermal nekroliz, pemphigus, shingles, alopecia, fotodermatit.

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Allergic reactions: syndrome Stevens - Johnson, rash, swelling Kvinke, anaphylactic shock, etc.
Other: raising body temperature, chills, sepsis, arthralgia, hyperpotassemia, ginekomastiya, serum sickness, increased content in the blood of liver enzymes, urea nitrogen, acidosis, a positive reaction in the test for antibodies to nuclear antigens.

Interaction: Potentsiruet gipoglikemichesky protivodiabeticheskih effect of oral drugs increases the potential hypotensive effect of anesthetics. Decreases secondary giperaldosteronizm and gipokaliemiyu caused by Diuretics. Increases concentration of lithium and digoxin in plasma. The effects of antihypertensive reinforce other means, including beta-adrenoblokatory, including Suction flow rates up in the system of ophthalmic dosage forms, diuretic means, Clonidine, narcotic analgesics, antipsychotic tools, alcohol, weakened - estrogeny, NPVS, simpatomimetiki, antatsidy (reduce the bioavailability of 45%). Kaliysberegayuschie Diuretics, tsiklosporin, potassium medications and supplements, salt substitutes, milk, low-salt increases the risk of hyperpotassemia. Drugs, depressing the function of bone marrow (immunosuppressant, cytostatics and / or allopurinol), increase the risk of NEUTROPENIA and / or agranulocytosis fatal. Enhances the depressant effect of alcohol on the central nervous system. Probenecid slows the ascent kaptoprila with urine.